Xipamide is a sulfonamide diuretic drug marketed by Eli Lilly under the trade names Aquaphor (in Germany) and Aquaphoril (in Austria). Xipamide is used to treat high blood pressure and fluid retention. It removes excess water from the body by increasing how much and how often you pass water. By removing fluid from the blood vessels also decreases the pressure within the blood vessels. This makes it easier for a weak heart to pump blood around the body. Diuretics act in the kidneys. They work by causing the kidneys to increase the amount of salts, such as potassium and sodium, that are filtered out of the blood and into the urine. When these salts are filtered out of the blood by the kidneys, they draw water alongside them. As diuretics increase the removal of salts from the blood, they also cause more water to be drawn out of the blood and into the urine. Sources: http://www.patient.co.uk/medicine/Xipamide.htm http://en.wikipedia.org/wiki/Xipamide http://www.netdoctor.co.uk/heart-and-blood/medicines/diurexan.html DRO-status: http://www.globaldro.com/uk-en/search/IngredientStatus.aspx?ingid=480&countryid=2&sportid=32&exact=1&searchid=721062&userid=1&show=All&search=Xipamide&newSearch=false